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Cell Repair & Regeneration Therapy (CRRT) is an innovative technological advanced form of therapy that uses a non-invasive medical device to treat osteoarthritis, osteoporosis, accident, sports and repetitive stress injuries. It involves directing a series of magnetic pulses through injured tissue. Each magnetic pulse induces a tiny electrical signal that stimulates cellular repair.
Cell Repair & Regeneration Therapy (CRRT) uses creates a low-power electromagnetic field through which an unique form of pulsed signals are directed to the affected area, to stimulate the healing of damaged structures such as cartilage, intervertebral discs, bones, the attachment points of tendons, ligament structures and the articular capsule within all joints. It has also been found useful in the treatment of osteoarthritis, osteoporosis, stress fractures and the mal-union of broken bones.
The effect of CRRT is based on the triggering of the body’s own regeneration through the physiological stimulus of signals transmitted by a low power electromagnetic field. CRRT forces a migration of positively charged hydrogen ions (H+) in the negatively charged extra cellular matrix.
The flow of charged particles, the hydrogen protons, affects the reconstruction of the electrical field (streaming potential) normally present around a joint and which is not only disturbed in arthritic patients, in tendonitis and injuries, but in nearly all orthopaedic conditions.
The development of CRRT technology was following an observation that certain pulsed electromagnetic fields could promote the healing of bone fractures that had failed to unite after a year or more as well as anecdotal reports that similar approaches could relieve pain and improve mobility in patients suffering from osteoarthritis and traumatic joint damage. Since existing PEMF devices had varied characteristics, an effort was made to determine whether a pulsed electromagnetic field with specific parameters that mimicked physiologic reparative activities might provide superior results. The normal stimulus for cartilage production and bone formation results from piezoelectric signals that generate a “streaming potential” in the extracellular matrix when skeletal structures are subjected to physical pressure.
CRRT is based on the application of a very specific type of pulsed electromagnetic field to bone and adjacent tissues. The CRRT device generates a pure magnetic field output signal that employs direct current with unidirectional biological frequencies below 30 Hz. The waveform is quasi-rectangular with measured field strengths generally below 2 mT or 20 Gauss. The system is controlled through a pulsed unidirectional magnetic DC field with multiple output frequencies implemented via a free-wheeling diode to optimize the inductance characteristics. Various frequency/amplitude combinations are switched over automatically and are transmitted under continuous control during the treatment period. Induction of treatment takes place during the first 10 minutes at half strength followed by a combination of pulsed signals that deliver the therapy at full strength over the remaining 50 minutes.
Over time, the joints of the human body become stressed by the continuous support of the body weight, muscle and tendon strength. The cartilage tissue reacts with a functional adaptation. It has been demonstrated that the cartilage layer of the joints under high load will become thicker and enable a more even distribution of the load. Electrical currents are responsible for the function of the cartilage cells and the regeneration of the bone tissue. However, in unhealthy cartilage tissue, a normal flow of streaming potentials is severely affected.
Activation of streaming potentials by CRRT
This signal stimulates the regeneration process in cartilage, tendons and ligaments
Alteration of the electrical field by osteoarthritis or injuries
Perturbation in the continued cartilage regeneration
Movements generate fine electric currents in the
Electrical field of the joint
Control of the constant preservation and regeneration of the cartilage and connective tissues (tendons, ligaments, etc.)
The patented Original CRRT technology intervenes here in the treatment of the affected joint cartilage. The unhealthy tissue is treated with impulses that constantly change in intensity and duration. Another effect of the pulsed electromagnetic fields method is that CRRT stimulates the natural regeneration of the cartilage cells and the bone tissue with changing rectangular impulses. The CRRT therapy concept supports natural processes and can be applied as a pain free, non-invasive method without known side effects.
The effect of CRRT is based on the triggering of the body’s own regeneration through the physiological stimulus of signals transmitted by a magnetic field. CRRT forces a migration of positively charged hydrogen ions (H+) in the negatively charged extra cellular matrix.
The flow of charged particles, the hydrogen protons, affects/ leads to the reconstruction of the electrical field (streaming potential) normally present around a joint and which is not only disturbed in arthritic patients, in tendonitis and injuries, but in nearly all orthopaedic conditions.
Research has shown that when stress is placed on a joint, a low power electrical signal is created. This natural signal tells the body to repair damaged or worn tissues and to maintain the health and proper functioning of the joint. Sometimes, this signal is disturbed as a result of aging, injury or disease. When this happens, the body is unable to repair the damage itself. This results in pain, inflammation and loss of proper function in the joint.
CRRT is unique in that it mimics the body’s natural signal, activating the normal healing process and stimulates the growth and repair of the damaged tissue.
When a joint is subjected to compressive stress, there is a displacement of the water present in the matrix accompanied by sodium ions, leaving the negative charges of proteoglycan molecules un-neutralised. By a mechanism of mechanical-electrical transduction, the mechanical stimulus is transformed into a weak electric current (potential streaming) which is thought to represent the main signal for the cartilage cells to increase the synthesis of proteoglycans and collagen. Bone and cartilage tissues have electromagnetic natural bio-potentials which are of crucial importance to the formation and the dynamic functional adaptation of the tissue. Various factors, including electrical stimuli such as pulsed electromagnetic fields, can activate the regeneration process. The combined energy parameters of CRRT belonging to the range is also observed in the connective tissue.
Early improvement of the joint function (mobility and flexibility) by the removal of muscular tension, with normalized joint kinematics and reduced pain
Acceleration of the healing process in injuries to joint-related structures
Stimulation of the chondrocyte activity on streaming potentials with regeneration of the cartilage tissue
Stimulation of the osteoblast activity through piezoelectric potentials with stabilisation of the bone thickness
If the potential streaming is the signal for chondrocytes to produce new matrix, the same effect can be obtained by exposing the joints to an electro-magnetic field, producing currents which stimulate those of the organism. Administration in this way of a low strength pulsed signals at a frequency similar to the biological one that is capable of creating an electrical field in the joint, prompting the regeneration of the cartilaginous tissue, and thus conferring physical chondroprotection.
Unlike traditional magnetic field therapy, with CRRT, the magnetic field only serves as the “carrier” for the electrically pulsed signals. The magnetic field allows these signals to penetrate the injury unchanged. Without the magnetic field, the pulsating signals would be distorted by varying density of the surrounding tissue.
PIC: Magnetic field therapy alternating current sinusoidal waveform
PIC: PEMF rectangular direct-current-oriented impulses
PST/CRRT signal therapy with Alternating rectangular pulses as physiological stimuli
| Device Parameter | Magnetic Field Therapy | CRRT |
|---|---|---|
|
Electromagnetic Properties
|
Piezoelectric |
Biological signal |
|
Energy Form |
Alternating Curren |
Direct Current |
|
Frequency
|
44-77 Hz |
1-30 Hz |
|
Wave-Form
|
Sinusoidal |
Quasi- Rectangular |
|
Field Strength |
2 Gauss |
12.5 Gauss
|
|
Energy Driver
|
Voltage Control |
Pulsed DC |
|
Duty Cycle |
<50% |
<50% |
|
Pulse Frequency |
Continuous |
Pulse Modulated |
|
Frequency Source |
Fixed Frequency Source
|
Six Frequency Sources |
|
Implementation
|
Diode (Biasing) |
Free- Wheeling diode |
|
Operational/ Functional variation |
Electromagnetic field is the source of Healing stimulation
|
pulsed electric impulses are key source for healing stimulation. Electromagnetic field is used only as a carrier to transmit the pulsed electric signals |
Research has shown that when stress is placed on a joint, a low power electrical signal is created. This natural signal tells the body to repair damaged or worn tissues and to maintain the health and proper functioning of the joint. Sometimes, this signal is disturbed as a result of aging, injury or disease. When this happens, the body is unable to repair the damage itself. This results in pain, inflammation and loss of proper function in the joint.
CRRT is unique in that it mimics the body’s natural signal, activating the normal healing process and stimulates the growth and repair of the damaged tissue.
CRRT treats arthritis, sports and repetitive stress injuries using a pulsed signal delivered through a non-invasive magnetic field. The treatment is administered in nine/ twelve one-hour, pain-free sessions conducted under the supervision of trained physicians or therapists. The goal is to reach both short- and long-term reduction of pain, improve physical resilience and increase joint function.
Because the procedure is totally non-invasive, patients can wear any style of clothing. During treatment, the patient sits or lies in a specially developed chair or bed. The relevant joint is positioned in the CRRT device so pulsed signals can be sent to the cartilage and connective tissue. Most patients feel no pain during the treatment. Some patients may feel a slight tingling or sensation of warmth in the area being treated, while others may temporarily experience a slight increase in the normal pain they feel in the affected area. This is considered a positive reaction brought about by the reconstruction and healing occurring in the injured area, and any discomfort usually disappears quickly.
About 75- 85% of patients receiving the treatment experience significant improvement, with reduced pain and improved joint function. CRRT does not provide instant relief or instant re-generation. It’s a progressive medical therapy where the growth of cartilage may progress until 9-10 months post therapy.
Arthritis of large and small joints
Tendonitis/ insertion tendinopathy
Lumbago, degenerative disc disease, discopathy
Calcaneal Spur
Deforming arthrosis of the hands
Gonarthritis, coxarthrosis, rhizomatic arthrosis of the thumb
Rheumatic Joint Diseases*
Metabolic Joint Damage (e.g. Gout) *
* Note: EMRT does not treat the underlying inflammatory disease, but offers a reduction in pain levels and an increase in mobility
Ligament lesions/ ruptures
Meniscus injuries
Fractures
Pseudo arthrosis
Soft Tissue Injuries
Indicated as a Post-Op treatment to sustain healing and improve functional rehabilitation.
Spinal Column (e.g. scoliosis**)
Ligament lesions/ ruptures
Foot (e.g. hallux valgus, hallux rigidus, splay foot, club foot, pes planus)
Arthrosis of the hands
CRRT applications pertains to pain and impaired function
Perthes Disease
Osteochondrosis Dissecans
Arthritis Treatment
Cartilaginous changes within the synovial membrane of a joint
Patients with Pacemakers
Patients with ferrous metal implants
Bacterial Infections
Cardiac Arrhythmias
Severe Cardiac Insufficiency
Suspected Tumour or a diagnosed cancer requiring radiation and/or chemotherapy in the past 5 years
Heavy Bleeding
Epilepsy
Pregnant Women
Children under the age of 10 years
Intraarticular Injections
Invasive Treatments
Manipulation of the Joint (chiropractic/ osteopathic/ physiotherapeutic measures, including traction table treatment and deep tissue massage)
Targeted joints: cervical spine, thoracic spine, lumbar spine, hip joints, shoulder joints, foot, knee, ankle, hand, wrist, elbow
Concept: This device has been specifically developed to treat large joints. The CRRT H-300 is equipped with a full body bed and a variable pitch coil. It has been designed in order to allow patients to be treated in the most relaxed position possible
Targeted joints: cervical spine, thoracic spine, lumbar spine, hip joints, shoulder joints, foot, knee, ankle, hand, wrist, elbow
Concept: This device is a miniature economical version of Full Body H-300 CRRT. This is a foldable & Moveable model.
Targeted joints: foot, knee, ankle, hand, wrist, elbow, shoulders
Concept: mobile/ portable version designed in order to respond to the needs of patients living far away from CRRT centres or who prefer to be treated in the comfort and convenience of their own home.
CRRT or PST is an exciting, non-invasive medical technology used to treat arthritis, sports-type injuries, and repetitive stress injuries. The technology produces an electromagnetic field through which a pulsed signal is directed to the affected area, stimulating the healing process.
These are electrical signals with a fixed structure and form which are repeated at specific intervals.
They reactivate the body’s own electrically controlled repair/regeneration system.
No, unlike magnetic field therapy, with CRRT the magnetic field only serves as the “carrier” for the electrically pulsed signals. The magnetic field allows these signals to penetrate the injury unchanged. Without the magnetic field, the pulsating signals would be distorted by varying density of the surrounding tissue.
No, it is totally non-invasive and most patients find it to be pain-free. The treatment is provided in a relaxed atmosphere with the patient fully clothed. Patients may sometimes feel a slight tingling or sensation of warmth in the area being treated. Some patients may temporarily experience a slight increase in the normal pain they feel in the affected joint. This is a positive reaction brought about by the reconstruction and healing occurring in the injured area.
No. The signal produced by the machine reproduces the signal already naturally present in the body. Thousands of patients have received CRRT since its introduction, with absolutely no side effects.
Researchers have discovered that when we place stress on a joint a low power electrical signal is created. They believe this natural signal tells the body to repair damaged or worn tissues and to maintain the health and proper functioning of the joint. Sometimes this signal is disrupted by disease, aging or injury. When that happens, the body is unable to repair the damage. The result is pain, inflammation, and loss of physical function. CRRT is able to mimic the body’s natural signal, activating the normal healing process and stimulating the growth and repair of the damaged tissue.
The technology used in CRRT is based on years of research and has been subjected to rigorous scientific review in university laboratories and medical schools. Results of these studies have been widely reported in the media and prestigious medical journals – contributing to the tremendous demand for CRRT in treating arthritis, sports and repetitive stress injuries.
The treatment is administered in nine/ twelve one-hour sessions. Patients near the treatment centre are typically treated one hour a day. For out-of-town patients, an expedited course of nine/ twelve treatments over a four to six-day period is available. It is important to note that multiple areas of the body may not be treated simultaneously, as this leads to a loss of effectiveness. In the event that more than one area must be treated, this must be performed consecutively.
CRRT has been used successfully by prominent professional athletes, amateur athletes, seniors and other patients who have had their quality of life compromised by arthritis, sports-type injuries and repetitive stress injuries. It is irrelevant whether the patient is young or old or whether the defects result from age, injury, chronic degeneration or inflammatory disease. As shown through studies and the results of thousands of actual cases, approximately 80% of patients experience a reduction in pain and inflammation combined with an increase in physical function. Some patients are free of all symptoms following treatment. Others find their symptoms greatly reduced. Many patients are able to cut back on their pain medication or discontinue it altogether. Patients have reported being able to return to normal routine activities, and many are able to again participate in their favorite sports. The biggest benefit for many patients is the ability to avoid the expense, pain and inherent risks of surgery.
Compared to surgery or the ongoing use of prescription medications, CRRT treatment is a relatively inexpensive therapy. Included in the cost are nine or twelve one-hour treatment sessions, consultation and evaluation by the physician, and all associated medical examinations. While travel and lodging costs are not included for out-of-town patients, special package programs are available.
Because the signal delivered through the device is of a very low energy range (one one-thousandth of the energy of an MRI machine) CRRT is extremely safe. In thousands of patients treated worldwide there have been absolutely no adverse side effects reported. However, as an additional precaution, based on ensuring the highest levels of safety, children, women who are pregnant, and cancer survivors who have received medical treatment for their disease within the past five years are not currently accepted for treatment. Treatment of patients with cardiac pacemakers is limited to the extremities.